AN UNBIASED VIEW OF MUSCULAR DYSTROPHY THERAPIES VASANT KUNJ

lately, the antibiotic gentamicin has been tested in boys with DMD, about ten% of whom have inherited a dystrophin gene having a untimely end codon that halts the synthesis with the protein N-terminal for the dystroglycan binding location. Gentamicin suppresses chain termination, enabling some whole-length dystrophin being produced. This brings abo